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Perfil de consumo de antineoplásicos injetáveis em um Hospital Universitário
Márcia Dias (1,2); Natalia Bousquet (1,2); Manuela Pedroza (3); Araken Caldas (2)
(1) Curso de Especialização Treinamento em Serviços para Farmacêuticos Hospitalares, nos moldes de Residência. Rua Mário Viana, 523 – CEP 24241-000 – Niterói (RJ)
e-mail: marciadias_35@yahoo.com.br, nataliabousquet@gmail.com
(2) Hospital Universitário Antônio Pedro (HUAP)
Rua Marquês de Paraná, 303 - CEP 24030-210 – Niterói (RJ)
e-mail: apcaldas@gmail.com
(3) Centro Universitário Plínio Leite (UNIPLI)
Av. Visconde do Rio Branco, 123 - CEP 24020-000 - Niterói (RJ)
e-mail: manu_pedroza@yahoo.com.br
Introdução: A Política Nacional da Assistência Farmacêutica juntamente com a Política Nacional de Medicamentos constituem um dos elementos fundamentais para a implementação de ações de melhoria das condições de assistência à saúde da população. A atenção farmacêutica envolve vários componentes inclusive o registro sistemático das atividades e avaliação de resultados.
Objetivo: Estimar o perfil de consumo de medicamentos antineoplásicos na central de quimioterapia do HUAP.
Método: As prescrições médicas de serviços ambulatoriais e de internação foram analisadas entre o período de abril a julho de 2008, considerando os antineoplásicos injetáveis padronizados e o número de manipulações deste período.
Resultados: Os medicamentos 5-fluorouracil (5-FU), citarabina (ARA-C), doxorrubicina (DOXO) e etoposido (VP16) apresentaram maior perfil de consumo nos meses estudados, acima de 100 frascos. O número de manipulações feitas no hospital no período foi em média aproximadamente 1140 por mês.
Discussão e Conclusão: Apesar de não ser um hospital especializado em oncologia, a crescente demanda de serviços em quimioterapia vem levando o staff farmacêutico hospitalar a determinar o perfil de consumo destes medicamentos para programar de forma correta a aquisição destes e assim, evitar tanto a demanda reprimida quanto a interrupção do tratamento.
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A partir da média mensal de manipulações de um período de quatro meses, foi possível determinar os antineoplásicos de maior consumo médio dentre os padronizados, cujo consumo em conjunto gira em torno de 63% do total de manipulações do período estudado. Nosso trabalho demonstra a importância do ciclo da atenção farmacêutica, em especial a programação, para a correta alocação de recursos públicos hospitalares.
Referência: 1º Congresso de Farmácia Hospitalar em Oncologia do INCA. Rio de Janeiro. 2008
09 fevereiro 2009
03 fevereiro 2009
Analysis of pharmaceutical interventions: Hospital Garcia de Orta
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Santos A, Rodrigues C, Alcobia A. Pharmacy Department, Hospital Garcia de Orta, EPE, Almada, Portugal. farmaceuticos@hgo.min-saude.pt
Background: A systematic record is made by the pharmacist of interventions to medical prescriptions in a unit dose drug distribution system. This is a practical method that enables communication between health professionals and allows the detection and resolution of drug-related problems, so enhancing clinical activity. The main objective of this study was to quantify and characterise the pharmaceutical interventions made in some wards of the hospital.
Methods: Prospective observational study of the pharmaceutical interventions that were made during review of the drugs prescribed from January to June 2006 in the gastroenterology, infectious diseases, rheumatology, neurology and vascular surgery departments.
Results: During the study period, 510 interventions were made in the following categories: 259 (51%) nonhospital formulary drugs, 58 (11%) drug substitution, 55 (11%) therapeutic drug monitoring, 54 (11%) antibiotic justifications, 34 (7%) wrong dosage, 16 (3%) drug stability, 9 (2%) drug information, 8 (2%) duplicate therapeutics, 8 (2%) drug interactions, 7 (1%) change from intravenous to oral administration and 2 (<0.5%) wrong indication. Of the 76 drugs studied, those that generated most interventions were: bisoprolol, valsartan, piperacillin–tazobactam, meropenem and vancomycin. All interventions mentioned previously were accepted by the medical staff, as were the suggested courses of action related to interventions.
Conclusions: Adjustment of dosage, drug monitoring and drug stability are just some of the interventions that result in improvements to the care provided to patients, as well as a better management of the available resources. The prevention of these problems must be a priority for the pharmacy department, whose main goal is to ensure the safety and efficacy of the drugs administered in the hospital environment. The next step will be to create a computerized record to classify these interventions and determine the clinical and economic impact of drug-related problems.
Reference: 13th Congress of the European Association of Hospital Pharmacists. 2008
Santos A, Rodrigues C, Alcobia A. Pharmacy Department, Hospital Garcia de Orta, EPE, Almada, Portugal. farmaceuticos@hgo.min-saude.pt
Background: A systematic record is made by the pharmacist of interventions to medical prescriptions in a unit dose drug distribution system. This is a practical method that enables communication between health professionals and allows the detection and resolution of drug-related problems, so enhancing clinical activity. The main objective of this study was to quantify and characterise the pharmaceutical interventions made in some wards of the hospital.
Methods: Prospective observational study of the pharmaceutical interventions that were made during review of the drugs prescribed from January to June 2006 in the gastroenterology, infectious diseases, rheumatology, neurology and vascular surgery departments.
Results: During the study period, 510 interventions were made in the following categories: 259 (51%) nonhospital formulary drugs, 58 (11%) drug substitution, 55 (11%) therapeutic drug monitoring, 54 (11%) antibiotic justifications, 34 (7%) wrong dosage, 16 (3%) drug stability, 9 (2%) drug information, 8 (2%) duplicate therapeutics, 8 (2%) drug interactions, 7 (1%) change from intravenous to oral administration and 2 (<0.5%) wrong indication. Of the 76 drugs studied, those that generated most interventions were: bisoprolol, valsartan, piperacillin–tazobactam, meropenem and vancomycin. All interventions mentioned previously were accepted by the medical staff, as were the suggested courses of action related to interventions.
Conclusions: Adjustment of dosage, drug monitoring and drug stability are just some of the interventions that result in improvements to the care provided to patients, as well as a better management of the available resources. The prevention of these problems must be a priority for the pharmacy department, whose main goal is to ensure the safety and efficacy of the drugs administered in the hospital environment. The next step will be to create a computerized record to classify these interventions and determine the clinical and economic impact of drug-related problems.
Reference: 13th Congress of the European Association of Hospital Pharmacists. 2008
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