15 junho 2014

IMPLEMENTATION OF A CLINICAL PHARMACY SERVICE AND ANALYSIS OF THE PHARMACOTHERAPEUTIC INTERVENTIONS IN THE NEUROLOGY SECTOR OF HCFMRP/USP

JOÃO PAULO VILELA RODRIGUES, LILIAN PEREIRA PRIMO, LORENA ROCHA AYRES, LEONARDO RÉGIS LEIRA PEREIRA, ALEXANDRA CRUZ ABRAMOVICIUS

Centro de Pesquisa em Assistência Farmacêutica e Farmácia Clínica, Universidade de São Paulo, Brasil - Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto (HCFMRP/USP), Universidade de São Paulo, Brasil

Introduction: Neurological diseases are common in the population and there is a lack of well defined protocols for the treatment of some of them. The management of drug therapy is also difficult in relation to toxicity, drug interactions and complexity of treatment. Clinical Pharmacy (CP) is a tool that can provide safe and effective therapies to hospitalized patients. The aim of this study is to describe the pharmacotherapeutic interventions (PI) conducted by clinical pharmacists and the degree of acceptance by physicians during the first year of this service implementation in Neurology Sector of Hospital das Clínicas de Ribeirão Preto (HCFMRP-USP).

Methods: We retrospectively revised pharmacists’ interventions records from 109 hospitalized patients between December, 2011 and December, 2012. We included adults of both sexes, regardless of the reason of admission. It was considered only the PI performed together with the medical staff that was documented.

Results: The CP team made 74 PI, of which 64 (86%) were accepted by the physicians. There were sixteen dose changes, twelve discontinuations due to adverse reactions and/or drug interactions, eighteen changes in forms of administration, nine discontinuation unnecessary and/or ineffective treatment, two changes in treatment period, four introduction of a new drug, nine drug or treatment changes and four pharmaceutical formulation changes.

Conclusion: The results show that CP is an important tool for the safety and effectiveness of the treatment of hospitalized patients, which is confirmed by the high degree of adherence from the medical team to the PI performed.

Rev.Bras. Farm. – 94 (4); 2013

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